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News

DxS grants molecular diagnostic technology licence to DiagnoCure

DxS : 11 September, 2007  (New Product)
DxS has granted a licence to DiagnoCure of Canada, for DxS's Scorpions molecular diagnostic technology.
The agreement enables DiagnoCure to gain access to Scorpions for the development of their GCC based molecular test for colorectal cancer.

Dr Timothy J Holzer, vice president of R&D of DiagnoCure said of the agreement 'The Scorpions molecular diagnostic technology has the potential to significantly improve productivity and lower cost with regard to the processing of our gene-based tests. Most importantly, we intend to make use of it in our new GC-C tests for colorectal cancer.'

The DiagnoCure test uses Scorpions to detect GC-C (guanylyl cyclase c), a gene that appears normally in cells lining the intestinal tract, but is found on the outside of the intestine when colorectal cancer has metastasized.

DxS's Scorpions technology is ideally suited for cancer in vitro diagnostics, the probes are highly sensitive, sequence-specific, bi-functional molecules containing a PCR primer covalently linked to a probe. Scorpion probes provide strong fluorescent signals, excellent sequence discrimination, short reaction times, and predictable probe design.

The interaction of the probe and the desired target occurs very rapidly and in advance of any competing side reactions such as the formation of internal secondary structures or re-annealing. The intra-molecular nature of the Scorpions reaction means that it is ideally suited for fast, quantitative, real-time PCR analysis.

Commenting on the agreement, Dr Stephen Little, chief executive officer for DxS, said, 'We are delighted to have finalised our Scorpions license arrangement with DiagnoCure. It is a confirmation of confidence in our unique molecular technology, by a recognised leader in the field of cancer diagnostics.'
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