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Guides
Biomarker
A biomarker is a substance used as an indicator of a biologic state. It is a characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. The links shown on this page feature the key word ′Biomarker’ in their stories:
World sepsis day sponsorship
Patient diagnostics company pledges its support for eliminating life threatening preventable disease for World Sepsis Day
World Sepsis Congress to take place in September
Conference to discuss the battle against Sepsis as a life threatening illness that affects over 20 million people per year
Study commences on chronic disease caused by trauma
The detection and diagnosis of chronic traumatic encephalopathy associated with sports and military injuries is the subject of a new clinical study by Aethlon Medical
Internet of Things advancements on show for healthcare
Enabling medical device technology for IoT connections to smartphone applications for reducing overprescribing antibiotics to feature as part of the Medica Show
High sensitivity detection of lung cancer mutations
Paper presented by EKF Diagnostics shows effective method of using in vivo liquid biopsy technology for isolating circulating tumour cells in patients with lung cancer
Researchers make inroads in early cancer detection
Aethlon Medical expands brain research discoveries to include isolation of glioblastoma biomarker and therapeutic target
Imaging system for disease marker visualisation
PerkinElmer Slide scanner’s advanced digital pathology capabilities support deeper understanding of diseases and development of more effective therapies
DNA enrichment kits available for research use
The PointMan DNA enrichment kits from EKF are available for the sensitive detection of certain cancer mutations
Microfluidic probe assists in cancer diagnosis
Scientists at IBM have developed a probe for the examination of biopsy samples to assist in the development of personalised cancer treatments
White paper available on hemoglobin analyzers
A paper on the evaluation of glycated hemoglobin analyzers has been published by EKF Diagnostics
Subsidiary group to focus on study of exosomes
Exosome Sciences to be involved in the diagnostics of serious diseases with the detection and analysis of exosomes in body fluids
Qiagen partners Exosome Diagnostics to develop biofluid sample preparation kits for personalized healthcare
Qiagen is partnering with Exosome Diagnostics to develop and commercialise high-performance sample preparation kits for the processing of nucleic acids from exosomes.
SRI International points to biomarker that could track Huntington's disease progression
A team of SRI International researchers demonstrates that measurements of electrical activity in the brains of mouse models of Huntington's disease could indicate the presence of disease before the onset of major symptoms.
Biomarker is identified in the 2013 ACC/AHA Guidelines for the Management of Heart Failure
The American College of Cardiology Foundation/American Heart Association Task Force jointly released the organizations's expanded clinical practice guideline for the management of patients with heart failure and has identified Critical Diagnostics' biomarker ST2 "not only predictive of hospitaliz
Life Technologies launches next generation of analytics power tools for cancer researchers
Life Technologies is introducing Oncomine Next Gen Sequencing Power Tools, an analytics offering that will allow cancer researchers to explore results from in-depth analysis of next generation sequencing (NGS) data, including data from The Cancer Genome Atlas.
AB SCIEX mass spectrometry solutions improves identification and quantitation performance
AB SCIEX unveils three new solutions for biological researchers to improve identification and quantitation of proteins, peptides, metabolites and lipids.
Qiagen expands biomarker pipeline of personalized healthcare companion diagnostics
Qiagen signs two agreements which adds new biomarkers involving glioblastoma, lymphoma and other cancers to Qiagen's expanding portfolio of potential companion diagnostics that is being developed to help doctors use a patient's genomic information to guide treatment decisions.
Health Diagnostic Laboratory releases new blood test tool to manage prediabetes
Health Diagnostic Laboratory, a CLIA-certified laboratory specialising in advanced cardiovascular and metabolic disease testing and health management, is launching a new blood test for stratifying prediabetic patients based on the Quantose insulin resistance markers discovered by Metabolon.
Oncotest partners Debiopharm Group to identify biomarker candidates
Oncotest and Debiopharm Group a Swiss-based global biopharmaceutical group, complete the first biomarker projects at Oncotest.
Firefly BioWorks expands multiplexed microRNA assay solutions
Firefly BioWorks is expanding the company's microRNA assay, FirePlex miRSelect, from a maximum of 23 multiplexed microRNAs to 68.
Quest Diagnostics unveils dementia diagnostic panel for aiding the diagnosis of suspected dementia
Quest Diagnostics is launching the first clinical test panel for aiding the diagnosis of suspected dementia due to treatable forms of cognitive impairment.
Study shows point-of-care biomarker improves diagnosis of AKI in the emergency department
Alere is reporting results of a study published in Critical Care that demonstrates that plasma neutrophil gelatinase-associated lipocalin (pNGAL), a biomarker that aids in the early detection of acute kidney injury (AKI), improved the diagnosis of AKI when added to clinical judgement.
Two studies demonstrate next generation sequencing from FPET tissue improve tumour analysis
Genomic Health is reporting the results of two studies demonstrating that DNA strand-of-origin information can help further refine the identification of prognostic biomarkers, and that tumour specific gene mutations can be effectively examined using archival fixed paraffin embedded tumour (FPET) tis
RayBiotech agrees neuroscience biomarker agreement with Banner Sun Health Research Institute
RayBiotech executes a master services agreement with Banner Sun Health Research Institute (BSHRI) of Sun City, Arizona, USA.
Automated workstation improves protein therapeutics process development
PerkinElmer is launching the JANUS BioTx Pro automated workstation for improved process development of protein therapeutics at the 12th Annual Protein Science Week (PepTalk), January 21–25 in Palm Springs, Florida, USA at booth 312.
Two reference labs sign up With Critical Diagnostics to offer Presage ST2 Assay for heart failure patients
Critical Diagnostics, a US-based biomarker company focused on cardiovascular diseases and Quest Diagnostics and its subsidiary Berkeley HeartLab, announced today an agreement under which both Quest and Berkeley HeartLab will offer ST2 testing services based on Critical Diagnostics’ Presage ST2 Assay
Nanoparticles technology aims to offer earlier cancer diagnosis solution
A new technology developed at MIT aims to help to make biomarker detection much easier with researchers, led by Sangeeta Bhatia, developing nanoparticles that can home in on a tumour and interact with cancer proteins to produce thousands of biomarkers, which can then be easily detected in the patien
Corgenix gains regulatory approval for sale of AspirinWorks in China
Corgenix Medical's AspirinWorks ELISA product has received notification of regulatory approval from the State Food and Drug Administration (SFDA) of the Peoples Republic of China.
Consortium receives funding to research Sepsis biomarkers
A consortium involving the University of Brighton is awarded about £400,000 for research into a diagnostic aid to combat one of the UK's biggest killers.
Novel cardiac biomarker helps predict progression of heart failure in chronic HIV-infected patients
A presentation at the American Heart Association Scientific Sessions in Los Angeles, California, USA reveals the results of a study that demonstrated elevated levels of the biomarker ST2 in HIV patients was strongly indicative of the development of heart failure and mortality.
Caris Life Sciences selects next-generation sequencer as part of molecular profiling service
Caris Life Sciences selects Illumina's MiSeq sequencing system to support Caris' evidence-based molecular profiling service. The MiSeq system will be deployed to enable rapid, simultaneous analysis of multiple genes from formalin-fixed, paraffin-embedded (FFPE) tumour tissues using Illumina's amp
ABT Molecular Imaging injects funds to continue growth of biomarker generator
ABT Molecular Imaging, a medical imaging company selling a production platform to generate unit doses of molecular imaging drugs, secures a $6 million round of financing.
Liquid chromatography instrument provides plug-and-play interchangeability
AB SCIEX launches the Eksigent ekspert nanoLC 400 system which claims the world's first plug-and-play liquid chromatography system that integrates nano LC and micro LC on the same platform, providing the broadest functionality with the benefits of both flow rate ranges.
Quotient and Pulmatrix completes COPD proof-of-concept clinical programme
Quotient Clinical and Pulmatrix, a clinical stage biotechnology company creating novel inhaled therapeutics, complete an early clinical programme to achieve proof-of-concept data in COPD patients for PUR118, Pulmatrix's lead iCALM (inhaled dry powder cationic airway lining modulator) therapeutic.
Critical Diagnostics extends presence in Asia Pacific Region for cardiac biomarker
Critical Diagnostics is continuing to expand the company's presence in the Asia Pacific region with the addition of two distribution partners.
Affymetrix launches RNA amplification technology for whole-genome expression analysis
Affymetrix is introducing SensationPlus FFPE Amplification and 3' IVT Labeling Kit (SensationPlus FFPE Reagent Kit), consisting of RNA amplification and labeling modules, to enable gene expression profiling of formalin-fixed, paraffin-embedded (FFPE) samples on GeneChip 3' IVT arrays and Almac Xcel
Affymetrix expands QuantiGene ViewRNA license for in vitro diagnostics
Affymetrix is expanding its license agreement with Siemens Healthcare Diagnostics for the company's branched DNA (bDNA) technology whereby Affymetrix is the exclusive licensee for in situ products, including in vitro diagnostics.
EKF signs exclusive licensing deal for novel kidney markers
EKF Diagnostics Holdings signs an exclusive license agreement with the Joslin Diabetes Center, a teaching, research and clinical care affiliate of Harvard Medical School, to license certain novel kidney biomarker technology.
GE Healthcare collaborates with CSIRO to research Alzheimer's Disease
GE Healthcare is collaborating with Australian Commonwealth Scientific and Industrial Research Organisation (CSIRO) involving its investigational PET imaging agent [18F flutemetamol].
Cardinal Health unveils new nuclear medicine technology enhancements
Cardinal Health is introducing new technology enhancements that make it possible for hospital nuclear medicine departments and imaging centres to seamlessly improve data integration and the overall efficiency of their operations.
Affymetrix collaborates with MGH to develop new oncology biomarkers
Affymetrix is making a research collaboration and licensing agreement with Massachusetts General Hospital (MGH) to co-develop new cancer biomarker tests using the Affymetrix' QuantiGene ViewRNA Assay platform, an in situ hybridization assay capable of single transcript in single-cell detection.
GE Healthcare licenses Insight Genetics genomic biomarker for lung cancer
Clarient Diagnostic Services, a GE Healthcare company, and molecular diagnostics company Insight Genetics, signs a worldwide licensing agreement for intellectual property from Insight Genetics, granting Clarient rights to develop a genetic test covering the ALK (anaplastic lymphoma kinase) biomarker
AB SCIEX launches the world's most sensitive mass spectrometer
AB SCIEX is introducing the AB SCIEX 6500 series which features the new AB SCIEX Triple Quad 6500 and QTRAP 6500 systems that are next-generation mass spectrometers delivering up to a 10x increase in sensitivity over the best-selling, high-performance triple quadrupole system on the market.
Qiagen partners Cardinal Health to offer molecular diagnostic solutions
Qiagen is collaborating with Cardinal Health to extend the company's portfolio of laboratory offerings to select US hospitals to include Qiagen automated laboratory systems and test kits for molecular diagnostics.
Aptiv Solutions releases new adaptive trial software
Aptiv Solutions is releasing the company's proprietary suite of adaptive trial software: ADDPLAN 6.0 PE which was specifically developed to support adaptive design and simulation for population enrichment trials.
Metamark reveals proof-of-concept for prostate cancer test
Metamark Genetics completes proof-of-concept (POC) for its biomarker prognostic test for prostate cancer.
New mutation detection assays confirm more than 241 mutations
Life Technologies is expanding the company's TaqMan Mutation Detection Assays which are sensitive and novel molecular analysis research tools designed to detect an additional 241 of the most common mutations in 21 cancer genes.
Almac signs global distribution deal with Affymetrix
Almac signs an exclusive global distribution deal with Affymetrix enabling the company to directly sell Almac's proprietary Xcel array for biomarker discovery, development and delivery worldwide.
Partners develop blood-based test for mild cognitive impairment
DiaGenic signs a research agreement to collaborate with GE Healthcare to develop a blood-based test using DiaGenic's peripheral gene expression profiling in patients with mild cognitive impairment, a disorder associated with risk for Alzheimer's Disease.
Roche selects ICON to support online medical image repository
ICON is selected by Roche as its technology partner for storing and managing medical images collected during the company's clinical research programmes.
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