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News

Accuray’s Monte Carlo Dose Calculation algorithm is cleared for launch

Accuray : 10 September, 2007  (New Product)
Accuray’s Monte Carlo Dose Calculation algorithm has received 510(k) clearance from the US Food and Drug Administration and is now commercially available worldwide.
The product was launch at the 9th Biennial European Society for Therapeutic Radiology and Oncology (ESTRO) meeting on Physics and Radiation Technology for Clinical Radiotherapy in Barcelona, Spain.

Treatment with radiation therapy or Radiosurgery requires a linear accelerator to deliver one or more X-ray beams to a target. Each beam is made up of trillions of photons, and each photon follows an individual path to the target. Traditional dose calculation methods assume all photons take a single path and therefore use a single calculation to represent the dose delivered by all photons.

Monte Carlo methods are considered the gold standard of probabilistic statistics. The Monte Carlo dose calculation method takes the probability and potential interactions for each individual photon into account when it calculates the dose being delivered by a single photon. The method then considers the probabilities for each of millions of photons to generate a dose calculation for the target and surrounding structures.

Previously, because of the repetition of algorithms and the large number of calculations involved, Monte Carlo dose calculations were time consuming to compute and therefore were difficult to employ in clinical settings. Now, by integrating various speed-up techniques, Accuray has developed a Monte Carlo dose calculation algorithm that can more quickly and precisely predict the dose of radiation that will be delivered to tumours.

“The clearance and commercial availability of Accuray’s Monte Carlo Dose Calculation algorithm is a significant milestone in the use of Radiosurgery to treat tumours anywhere in the body, particularly lung tumours” said Euan S Thomson, PhD, president and CEO of Accuray. “We are extremely excited to be the first to market with a Monte Carlo dose calculation algorithm for photon beam radiation treatment that is capable of calculating the results within minutes. Now our customers will have access to the most state-of-the-art Radiosurgery system with the most cutting-edge dose calculation algorithm. ”

The Monte Carlo dose calculation methodology is ideal for use in treating lung tumours, which are solid masses surrounded by air cavities, because it takes into account varying tissue densities. By integrating the Monte Carlo Dose Calculation algorithm with the CyberKnife Robotic Radiosurgery System, Accuray offers clinicians one of the most advanced tools available today for treating lung cancer.

“Current dose calculation algorithms work well for treating most tumours because the surrounding tissue is relatively uniform, but assumptions had to be made within areas like the lungs and sinuses where tissue densities differ,” said Charlie Ma, PhD, director of radiation physics at Fox Chase Cancer Center in Philadelphia, who helped develop this customised version of Monte Carlo dose calculation for the CyberKnife System. “Now Accuray’s Monte Carlo Dose Calculation algorithm provides the most accurate physics-based model of radiation transfer available to date and the system is capable of computing complex dose distributions within minutes. This is a significant step forward in cancer treatment. ”

The Monte Carlo Dose Calculation capability will be available for purchase as a software upgrade for customers with the Multiplan 2.0 Treatment Planning System and is scheduled to begin shipping toward the end of this calendar year. For customers who do not already have the MultiPlan 2.0 System, the Monte Carlo Dose Calculation feature will be available to them with the purchase of a MultiPlan 2.0 System.

The new feature will also be available to customers who have previously signed Accuray’s Diamond Elite Service Agreement. The Diamond Elite Service Agreement enables customers to choose the right upgrades to fit their clinical strategy. Unlike traditional industry service programs, Accuray’s Diamond Elite Service Agreement maintains client investments with obsolescence protection, which ensures their systems’ clinical capabilities remain at the forefront of technological advances.

'With Accuray's service programme we've been able to upgrade our system with the latest technologies as soon they become available - keeping our CyberKnife System on the cutting edge,” said Alan Beckman, MD, chief of radiation oncology at Central Baptist Hospital in Lexington, Kentucky, USA. “Through the service agreement we look forward to acquiring the new Monte Carlo Dose Calculation feature in order to enhance our CyberKnife practice even further with this gold standard capability.'
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