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Cepheid begins shipping next generation molecular diagnostic systems

Cepheid : 08 January, 2008  (New Product)
Cepheid has begun to ship the next generation GeneXpert Systems including the new GX-I single module system featuring a six-colour optical capability that enables detection of up to 60 individual targets in a single cartridge.
The systems will also feature new software that enables Laboratory Information System (LIS) integration capabilities, linking any GX-I, GX-IV and GX-XVI System to healthcare institutions' central database for receiving, processing and storing test results.

The release of these enhancements follows a strong fourth quarter performance that saw 125 diagnostic GeneXpert System placements in Europe and the USA during the quarter. The system placements were comprised of 783 GeneXpert module installations.

'These new system enhancements are expected to further increase the utility of the GeneXpert System in processing data output and in achieving a high level of multiplex testing, which will be applied to infectious disease and oncology diagnostics,' said Cepheid CEO John Bishop. 'Additionally, these enhancements are expected to provide long-term benefits as our menu of tests grows, from infectious disease testing through oncology, and into broad-based genetic disease testing.'

The new GeneXpert System six-colour optics capability enables advanced multiplexing, making it possible to detect more molecular targets within a single test cartridge. The configuration of the GeneXpert cartridge allows for two reactions per test, which means that a total of 60 targets will be possible. The two-reaction capability also allows for reflex testing, in which the first test result indicates and automatically initiates a second related and potentially necessary diagnostic test.

Reflex testing is particularly important in clinical applications where results can guide treatment decisions, such as for the detection of infectious disease where the first reaction tests for the organism and the reflex test identifies the specific strain susceptible to drug resistance.

All current GeneXpert-based tests, including Xpert MRSA, are compatible with the new six-colour modules. Additionally, existing customers can expand their current GeneXpert Systems with the new six-colour modules by adding to, or replacing, their four-colour modules. The GeneXpert System software is capable of managing both four-colour and six-colour module types within the same GeneXpert System configuration.

The next generation GeneXpert Systems also include GeneXpert Software 2.1, an easy-to-use application that synchronises test data between any GeneXpert System and LIS. Upon completion of a test, the GeneXpert System may automatically upload test results to the LIS, providing healthcare professionals with rapid, actionable results as soon as they are available.

By eliminating manual entries and paper-based workflows, the new GeneXpert Systems improve the efficiency of transactions and may reduce the chance of transcription errors. Software upgrades are available to existing customers.
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