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InnerCool unveils new surface temperature modulation system

Cardium Therapeutics : 19 October, 2007  (New Product)
Cardium Therapeutics and its operating unit InnerCool Therapies have launched a new surface temperature modulation system that is designed to provide a complementary tool for use with less acute patients or in clinical settings best suited to prolonged temperature management.
InnerCool's new CoolBlue surface temperature modulation system features a console and a disposable CoolBlue vest with upper thigh pads.

InnerCool's CoolBlue vest and thigh pads wrap the body without requiring any adhesives to stick to the skin and produce cooling rates of around one degree C per hour, that is similar to those of currently marketed surface cooling systems and endovascular systems using inflatable balloon-based catheters.

'We are pleased to launch our new CoolBlue temperature modulation system. Nurses attending initial focus groups relayed their dissatisfaction and concerns with existing systems that require pads that adhere directly to a patient's skin. As a result, the CoolBlue pads are designed with a soft fabric inner lining and attach simply using Velcro strips,' stated Christopher J Reinhard, chairman and chief executive officer of Cardium Therapeutics and InnerCool Therapies.

'With our new CoolBlue surface temperature modulation system, our current endovascular Celsius Control System, and our next-generation RapidBlue endovascular system which is expected to be launched in first quarter 2008, we are in a unique position to provide hospitals with a one-source solutions approach to effective patient temperature modulation. With our comprehensive product portfolio, hospitals can employ our high performance rapid-cooling endovascular approach that uses a slim, flexible, heparin coated, metallic Catheter with an integrated temperature sensor for acute needs, followed by prolonged temperature management using our surface cooling system. With only an estimated 300 hospitals of 5,700 hospitals in the USA using cooling systems, we believe there is a significant opportunity to expand and accelerate the growth of InnerCool's temperature modulation business.'

'We recently evaluated the CoolBlue System in some of our patients in the intensive care unit and found the system to be easy to use and efficient in reducing fever burden,' stated Dr David LeDoux, director of Neuro Critical Care at North Shore University Hospital, Manhasset, New York.

'We plan to implement the CoolBlue system in our hospital as a standard of care for reducing body temperature.'

Patient temperature modulation is a rapidly-advancing field focused on preserving ischemic tissue and improving patient outcomes following major medical events such as stroke, cardiac arrest and heart attack, as well as in the management of patients experiencing trauma or fever.

Temperature modulation is intended to cool patients in order to reduce cell death and damage caused by ischemic events in which blood flow to critical organs such as the heart or brain is restricted, and to prevent or reduce associated injuries such as adverse neurologic outcomes.

InnerCool's CoolBlue external or surface-based temperature modulation system is designed to cool or warm patients from outside of their bodies and is intended for use in less acute settings such as in-hospital fever management.

InnerCool's next-generation RapidBlue system for high-performance endovascular temperature modulation, which is scheduled for launch in first quarter 2008, includes a programmable console with an enhanced user interface and a Catheter designed to quickly modulate patient temperature in association with surgery or other medical procedures.

The RapidBlue system powers InnerCool's Accutrol catheter, which has a flexible metallic temperature control element and a built-in temperature feedback sensor to provide fast and precise patient temperature control.
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