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Legacy Good Samaritan Hospital demonstrates breast-specific gamma imaging benefits

Dilon Technologies : 30 April, 2008  (Application Story)
A group of surgeons from Legacy Good Samaritan Hospital in Portland, Oregon, USA, have demonstrated the value of using Breast-Specific Gamma Imaging (BSGI) for the clinical management of breast cancer patients.
The data has been published in The American Journal of Surgery.

The breast centre's first year's experience with BSGI showed the upside of using physiological data obtained from the functional imaging of BSGI over imaging techniques that convey mostly anatomical data - such as mammography, Ultrasound and MRI. Specifically, the results of the study showed that BSGI:

- Changed patient management in 14 percent of the cases;

- Detected cancer in two percent of patients with no mammographic findings;

- Detected additional cancers in six percent of patients with known breast disease;

- Correctly ruled out the need for biopsy in 86 percent of patients with suspicious mammograms;

- Had a false positive rate of only six percent, as compared to 78 percent in acomparable MRI study.

The surgeons noted that breast density can cause the effectiveness of mammography to greatly decrease, so other imaging tests are needed to help address this group of high-risk patients. BSGI is not affected by breast density and has exhibited not only high sensitivity for detecting cancer, but also a strong ability to help rule it out.

In the retrospective study, performed by Dr Nathalie Johnson and colleagues, BSGI was determined to play an important role in their management of patients with complex breast tissue and newly diagnosed cancers. In addition, Legacy Good Samaritan Hospital noted that cost of BSGI was one-third that of MRI for their facility.

Dr David Maccabee, a surgeon practicing in Hood River, Oregon, stated, the data was clinically relevant and may change the way surgeons practice surgery in the future.

Dilon Technologies’ Dilo 6800, is a high-resolution, small field-of-view gamma camera, optimised to perform BSGI, a molecular breast imaging procedure which images the metabolic activity of breast lesions through radiotracer uptake.
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