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News

New clinical study focuses on the sensitivity of PEM technology for detecting small cancers

Naviscan PET Systems : 16 June, 2008  (Company News)
Naviscan PET Systems, a company specialising in organ-specific high resolution PET scanners, has released new clinical data based on the use of the PEM Flex scanner in breast cancer management.
The PEM Flex Solo II is a commercially available, FDA cleared scanner that utilises PET technology for the breast application known as positron emission mammography, PEM.

The results were presented at the Society of Nuclear Medicine's Annual Meeting from an independent study of 136 patients comparing the accuracy of PEM and MRI in the pre-surgical planning of breast cancer patients indicated the PEM technology is more sensitive than MRI in detecting the smallest cancers. PEM demonstrated 91 percent sensitivity in ductal carcinoma in situ (DCIS) compared to 83 percent with MRI and better sensitivity in cancers less than 5mm in size. PEM also detected a 2mm DCIS case shown to be negative on MRI.

'In our research, PEM accurately detected and characterised the smallest and most difficult to see cancers - specifically DCIS, which is often impossible to see with other imaging modalities,' said Kathy Schilling, MD and medical director of the Center for Breast Care in Boca Raton, Florida, who has been studying PEM for more than two years. 'The ability to image and diagnose these early stage cancers provides the potential for cure and will significantly impact breast cancer management.'

Dr Schilling has been using the PEM Flex scanner in her practice as a tool for evaluating additional and unsuspected disease in the breast and compares these findings with that of MRI. She is also a site principal investigator in a 400 patient, multi-centre clinical trial comparing PEM and MRI in breast cancer patients to be completed in 2008.

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