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New fully automated system developed to handle 4-plex microarrays

Tecan Group : 18 October, 2007  (New Product)
The QuadChamber has been developed by Tecan to provide fully automated processing of four different microarrays simultaneously on one slide, using the HS Pro automated hybridisation station.
The unit has been specially developed for use with Agilent's new 4x44k 4-plex gene expression as well as CGH microarrays, which consist of four individual, whole-genome microarrays printed on a single glass slide.

The new QuadChamber is the first fully automated system to independently handle four arrays on one slide with no cross-contamination between the arrays. Tecan and Agilent will present the system at the American Society of Human Genetics meeting in San Diego, California, USA, on October 23 to 27, 2007.

The QuadChamber provides a completely sealed environment around each of the four arrays on Agilent's 4-plex slides, with independent channels for wash buffers, independent agitation mechanisms and drying for each of the four areas.

With the new chamber, the HS Pro fully automates the hybridisation of the arrays from start to finish while maintaining separate compartments around each array on the slide.

The system ensures high quality processing with minimal slide handling, excellent reproducibility and bubble-free hybridisation through Tecan's active bubble suppression (ABS) technology.

The QuadChamber has already begun shipping.

Agilent's 4-plex microarrays concentrate sample hybridisation, so provide enhanced sensitivity and allow the detection of even very low abundance transcripts.

Having four arrays on each slide allows researchers to generate more genomics data per experiment while reducing the required volumes of samples and reagents.

“Agilent and Tecan have worked closely together to develop a fully-automated solution that provides high quality data and consistently good results,” said Jeff McMillan, Agilent product manager, genomics automation.

“Now, customers can combine the economies of four microarrays per slide with the benefits of automated hybridisation.”

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