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News

Olympus offers complete thyroid panel for immunoassay system

Olympus America : 15 April, 2008  (New Product)
Olympus has introduced a T-Uptake assay to now offer a complete thyroid panel for use with its AU3000i immunoassay system.
The AU3000i can now support TSH, T4, fT4, T3, fT3 and T-Uptake assays.

Screening of thyroid function is often indicated in persons with signs or symptoms of hypothyroidism, subclinical hypothyroidism, diabetes mellitus or hyperthyroidism, along with those who have had previous thyroid surgery or neck irradiation, the elderly, and others. It has been reported that about five percent of the US adult population has thyroid disease or is taking thyroid medication (Ref 1 and 2).

Consequences of untreated hyperthyroidism include atrial fibrillation, congestive heart failure, osteoporosis, and neuropsychiatric disorders. Hypothyroidism can cause symptoms that reduce the functional status and quality of life, such as depression or weight gain.

The T-uptake Assay measures the saturation of thyroid hormone binding capacities in a patient specimen. For diagnostic purposes the Olympus T-Uptake results should be used in conjunction with an Olympus Total T4 determination to yield the FTI. On-board stability for thyroid assays is 28-days and turnaround time is 28-minutes to first result. AU3000i reagents feature 2D barcodes for secure and convenient on-board reagent management.

The AU3000i system has throughput up to 240 tests per hour, random access processing, magnetic particle capture and chemiluminescent detection.

Ref 1 - Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, et al. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2002;87:489-99. [PMID: 11836274]

Ref 2 - Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The Colorado thyroid disease prevalence study. Arch Intern Med. 2000;160:526-34. [PMID: 10695693]
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