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News

Phytronix partners Thermo Fisher Scientific to offer high-speed LDTD technology

Thermo Fisher Scientific- Chromatography : 13 November, 2007  (New Product)
Thermo Fisher Scientific has formed a strategic partnership with Phytronix Technologies, a Canadian company, for the use of Laser Diode Thermal Desorption (LDTD) technology.
LDTD technology enhances the existing Thermo Scientific TSQ Quantum LC/MS product portfolio by offering ultra fast sample analysis for both quantitative and qualitative applications in high-throughput drug discovery, drug development, food safety and environmental applications.

The technology, consisting of a semiconductor based laser diode, allows scientists to rapidly analyse compounds. Simply loading the Phytronix Lazwell 96-well plate with the sample and then inserting the plate into the LDTD ion source operating at atmospheric pressure enhance the workflow.

The LDTD technology increases the speed of analysis of compounds by 20 to 100 times compared to established techniques based on liquid Chromatography with mass spectrometry. Pharmacokinetic studies using LDTD technology can be performed in less than 10 minutes, and enzyme inhibition assays in 18 minutes - compared to 10 hours presently required with LC-MS techniques.

The LDTD ion source utilises an infrared laser diode to thermally desorb the dried sample. The desorbed sample is transferred in the APCI region where it is ionised and then transferred into the MS. When configured with the TSQ Quantum, the system delivers fast and efficient quantitative and qualitative results.

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