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News

Senesco contracts with VGXI to supply Factor 5A plasmid

Senesco Technologies : 04 July, 2008  (Company News)
Senesco Technologies has contracted with VGXI to supply the plasmid portion of the company's combination therapy consisting of the Factor 5A gene and siRNA against Factor 5A.
Senesco has previously reported positive preclinical in vivo results using its combination siRNA and plasmid against subcutaneous multiple myeloma tumours in immunodeficient mice. The Factor 5A plasmid being produced by VGXI, as Senesco's preclinical data has shown, should cause cancer cells to enter apoptosis, or programmed cell death.

'VGXI's manufacturing and technical expertise in producing plasmids for Senesco's planned toxicology study and ultimately our clinical trial led us to choose them. We are pleased to be working with a company that has such an outstanding reputation in the field,' commented Bruce Galton, Senesco's president and chief executive officer.

Henry Hebel, vice president of operations for VGXI said, 'We believe that our ability to quickly supply the preclinical and clinical needs of our clients will allow Senesco to rapidly advance their programs. We are continuing to expand our collaborative development services to meet the growing needs for a wide variety of plasmid based products.'
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