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News

Thermo Fisher Scientific forms partnership with Vascular Proteomics Group at King's College London

Thermo Fisher Scientific Mass Spectrometry : 31 January, 2008  (New Product)
The newly opened Vascular Proteomics Group at the James Black Center, King's
College London, headed by Dr Manuel Mayr, has formed a collaborative partnership with Thermo Fisher Scientific.
Started in June 2007, the facility is equipped with the powerful combination of a Thermo Scientific LTQ Orbitrap XL high performance Mass spectrometer and the ETD-equipped Thermo Scientific LTQ XL system. This offers the most advanced proteomics capabilities available to today's researchers.

The James Black Center is a world-renowned research facility with a range of
core competencies including genomics, proteomics, mulitphoton confocal
microscopy and MRI. The Center is using the Thermo Scientific LTQ Orbitrap
XL, a protein identification and Biomarker discovery platform, along with an
LTQ linear ion trap coupled with electron transfer dissociation (ETD)
capability for advanced proteomic research in cardiovascular medicine.

'We are delighted that our new proteomics facility at the James Black Center
will feature cutting-edge technology dedicated to cardiovascular research.
Our primary focus will be on the ability of stem cells to affect
cardiovascular repair,' said Dr Mayr.

Professor Qingbo Xu, British Heart Foundation Professor at King's College
London, stated that, 'This group has the potential to make a big impact in
cardiovascular proteomics. The Cardiovascular Division has just been awarded
a 9 million grant from the British Heart Foundation, which will provide excellent
research possibilities here at King's College.'

The Thermo Scientific LTQ Orbitrap XL provides unparalleled sensitivity in
MS/MSn, a rapid scan rate, high mass accuracy and up to 100k resolution
power. Taking advantage of the high ion storage capacity and fast cycle
times of linear ion trap technology, the Thermo Scientific LTQ XL with ETD
enables researchers at Kings College to conduct rapid alternating CID
(Collisionally Induced Dissociation) and ETD experiments in LC/MSn analysis
of complex samples. By rapidly alternating the two fragmentation techniques,
it is possible to significantly increase proteome coverage and have complete
confidence in each protein identified.

At the opening, Thermo Fisher Scientific's UK Life Science sales manager,
Eric Winter, said 'Manuel Mayr and the Vascular Proteomics Group at King's
College are on the leading edge of proteomic research in cardiovascular
medicine. We are proud to provide complete workflow solutions for advanced
protein discovery proteomics and quantitation.'

Together, Dr Mayr and Thermo Fisher Scientific have already collaborated on
articles in Molecular and Cellular Proteomics and the Journal of the
American College of Cardiology, as well as a chapter in the Proteomics
Protocols Handbook.

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