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News

VTT begins Type 1 diabetes prevention study with Turku University Hospital and the Gothenburg University

VTT Technical Research Centre Of Finland : 02 October, 2008  (Company News)
VTT has begun a new three-year project with the Turku University Hospital and the Gothenburg University that aims to prevent Type 1 diabetes.
To achieve this goal the scientists will be using gut microbiota as a target.

The project is motivated by VTT's discovery of early metabolic signatures predictive of later progression to autoimmunity and type 1 diabetes. These metabolic signatures suggest the potential role of gut microbiota in early T1D pathogenesis. The project aims to discover specific microbes or lack of them associated with later progression to Type 1 diabetes, and to utilise that information for developing new prevention strategies. If the tests for the prevention strategies are successful the intervention can be considered for clinical stages.

The project is initiated and coordinated by Prof Matej Oresic from VTT. The project combines expertise in systems biology and metabolomics (VTT), clinical Type 1 diabetes research (Prof Olli Simell and his group from the Turku University Hospital and the Finnish Type 1 Diabetes Prediction and Prevention Study DIPP), and microbiology (Prof Fredrik Backhed, University of Gothenburg).

The gut microbiota as a novel target for prevention of type 1 diabetes project is coordinated by VTT and funded by the Juvenile Diabetes Research Foundation in USA.

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